Depo-Medrol Injection 40 mg Vial 10 mL by Hospira Pfizer (Rx)Depo Medrol 40 mg Depo Medrol is a brand name for methylprednisolone acetate, a long acting corticosteroid. It is supplied as a white oral suspension and given by injection (intramuscular (IM) or into a joint tissue) by a healthcare professional. Depo Medrol works as a potent anti inflammatory steroid, suppressing immune and inflammatory responses. In the official prescribing information, it is described as an anti inflammatory glucocorticoid for